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Franco Borsini Selected Research

9- piperazin- 1- ylpyrrolo(2,1- b)benzothiazepine

10/2008Haloperidol both prevents and reverses quinpirole-induced nonregulatory water intake, a putative animal model of psychogenic polydipsia.
9/2008Olanzapine (LY170053, 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine), but not the novel atypical antipsychotic ST2472 (9-piperazin-1-ylpyrrolo[2,1-b][1,3]benzothiazepine), chronic administration induces weight gain, hyperphagia, and metabolic dysregulation in mice.
5/2008ST2472: a new potential antipsychotic with very low liability to induce side-effects.

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Franco Borsini Research Topics

Disease

8Parkinson Disease (Parkinson's Disease)
07/2015 - 10/2006
4Catalepsy
08/2015 - 10/2006
3Pain (Aches)
08/2012 - 06/2012
3Alzheimer Disease (Alzheimer's Disease)
07/2011 - 07/2002
2Schizophrenia (Dementia Praecox)
07/2015 - 10/2008
2Anxiety Disorders (Anxiety Disorder)
01/2015 - 09/2002
2Neuralgia (Stump Neuralgia)
07/2012 - 06/2012
2Body Weight (Weight, Body)
04/2011 - 05/2010
2Heart Failure
04/2011 - 01/2007
2Polydipsia
09/2010 - 10/2008
1Colitis
03/2014
1Ulcerative Colitis
03/2014
1Inflammation (Inflammations)
03/2014
1Dementia (Dementias)
01/2013
1Acute Pain
07/2012
1Hyperalgesia
07/2012
1Torsades de Pointes (Torsade de Pointes)
06/2012
1Osteosarcoma (Osteogenic Sarcoma)
06/2012
1Mental Disorders (Mental Disorder)
10/2011
1Anhedonia
10/2011
1Memory Disorders (Memory Loss)
07/2011
1Gliosis
03/2011
1Graft vs Host Disease (Graft-Versus-Host Disease)
10/2010
1Pulmonary Aspergillosis
10/2010
1Peripheral Arterial Disease
03/2010
1Intermittent Claudication
03/2010
1Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome)
05/2009
1Myocardial Infarction
10/2008
1Psychogenic Polydipsia
10/2008
1Left Ventricular Dysfunction
10/2008
1Weight Gain
09/2008

Drug/Important Bio-Agent (IBA)

52- n- butyl- 9- methyl- 8- (1,2,3)triazol- 2- yl- 9H- purin- 6- ylamineIBA
08/2015 - 10/2006
5Adenosine A2A Receptor (Adenosine A2A Receptors)IBA
07/2015 - 07/2007
4Haloperidol (Haldol)FDA LinkGeneric
08/2015 - 10/2006
4Levodopa (L Dopa)FDA LinkGeneric
08/2015 - 10/2006
4serotonin 6 receptorIBA
07/2015 - 07/2011
3Pharmaceutical PreparationsIBA
01/2015 - 07/2007
3Antipsychotic Agents (Antipsychotics)IBA
01/2013 - 09/2008
39- piperazin- 1- ylpyrrolo(2,1- b)benzothiazepineIBA
10/2008 - 05/2008
2Oxidopamine (6 Hydroxydopamine)IBA
08/2015 - 08/2007
2Cannabinoid Receptors (Cannabinoid Receptor)IBA
01/2015 - 08/2012
2fatty-acid amide hydrolase (fatty acid amide hydrolase)IBA
01/2015 - 07/2012
2Anti-Anxiety Agents (Anxiolytics)IBA
01/2015 - 09/2002
21-biphenyl-4-ylethenyl piperidine-1-carboxylateIBA
01/2015 - 07/2012
2Carnitine (L-Carnitine)FDA LinkGeneric
03/2014 - 03/2010
2Biological ProductsIBA
07/2013 - 09/2010
2Antidepressive Agents (Antidepressants)IBA
01/2013 - 09/2002
2Peptides (Polypeptides)IBA
06/2012 - 08/2009
2Serotonin (5 Hydroxytryptamine)IBA
10/2011 - 09/2002
2IstaroximeIBA
04/2011 - 01/2007
2Purinergic P1 Receptor AntagonistsIBA
02/2011 - 05/2009
2Clozapine (Clozaril)FDA LinkGeneric
09/2010 - 10/2008
2Olanzapine (Zyprexa)FDA Link
10/2008 - 09/2008
2BenzodiazepinesIBA
09/2008 - 09/2002
1ST3932IBA
08/2015
1ST4206IBA
08/2015
1BenserazideIBA
08/2015
1EnzymesIBA
01/2015
1AntioxidantsIBA
03/2014
1Nitric Oxide (Nitrogen Monoxide)FDA Link
03/2014
1PropionatesIBA
03/2014
1Purinergic P1 Receptors (Adenosine Receptor)IBA
07/2013
1Monoamine Oxidase (MAO)IBA
02/2013
1pyrimidineIBA
02/2013
1LigandsIBA
01/2013
1cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester (URB597)IBA
07/2012
1EndocannabinoidsIBA
07/2012
1CarbamatesIBA
07/2012
1AcidsIBA
07/2012
1Pregabalin (Lyrica)FDA Link
07/2012
1dofetilide (Tikosyn)FDA Link
06/2012
1Calcitonin Gene-Related PeptideIBA
06/2012
1Neurotransmitter Agents (Neurotransmitter)IBA
06/2012
1palmitoyl- glutamyl- glutamyl- methionyl- glutaminyl- arginyl- argininamideIBA
06/2012
1Ion Channels (Ion Channel)IBA
06/2012
1Proteins (Proteins, Gene)FDA Link
06/2012
1Freund's AdjuvantIBA
06/2012
1Chloroquine (Aralen)FDA LinkGeneric
06/2012
1Analgesics (Analgesic Drugs)IBA
06/2012
1SugarsIBA
10/2011
12- (5- chloro- 2- methyl- 1H- indol- 3- yl)- N,N- dimethylethanamineIBA
10/2011
1Serotonin ReceptorsIBA
07/2011
11- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
03/2011
1Cholinergic Agents (Cholinergics)IBA
02/2011
1CortisoneFDA Link
10/2010
1Adrenal Cortex Hormones (Corticosteroids)IBA
10/2010
1Nonesterified Fatty Acids (NEFA)IBA
05/2010
1Amyloid beta-PeptidesIBA
08/2009
1Amyloid (Amyloid Fibrils)IBA
08/2009
1Neuroprotective AgentsIBA
05/2009
1Adrenergic beta-Agonists (beta-Adrenergic Agonists)IBA
10/2008
1N(1)-methyl-2-lysergic acid diethylamide (MIL)IBA
10/2008
1DobutamineFDA LinkGeneric
10/2008
1Clomipramine (Anafranil)FDA LinkGeneric
10/2008
1QuinpiroleIBA
10/2008
1Milrinone (Primacor)FDA LinkGeneric
10/2008

Therapy/Procedure

3Therapeutics
05/2009 - 07/2007
1Drug Therapy (Chemotherapy)
06/2012
1Immunotherapy
08/2009
1Injections
10/2008